RecruitingNCT00626496

Family Study of Lymphoproliferative Disorders

Genetic Epidemiology of Lymphoproliferative Disorders

Sponsor

Mayo Clinic

Enrollment

3,000 participants

Start Date

Apr 1, 2004

Study Type

OBSERVATIONAL

Conditions

Multiple Myeloma Lymphoma, Non-Hodgkin Lymphoma, B-Cell Leukemia, Lymphocytic, Chronic, B-Cell Monoclonal B-Cell Lymphocytosis

Summary

Blood and lymph node cancers can begin in either the lymphatic tissues (as in the case of lymphoma) or in the bone marrow (as with leukemia and myeloma), and they all are involved with the uncontrolled growth of white blood cells. There are many subtypes of these cancers, e.g., chronic lymphocytic leukemia and non-Hodgkin lymphoma. Since there is evidence that these cancers cluster in families, this study aims to understand how genetics and environmental exposures contribute to the development of these cancers.

Eligibility

Min Age: 18 YearsMax Age: 100 Years

Plain Language Summary

Simplified for easier understanding

This family-based study is looking for inherited genetic factors that increase the risk of lymphoproliferative disorders — a group of conditions where the body produces too many lymphocytes (white blood cells), including various types of lymphoma and leukemia. **You may be eligible if...** - You have been diagnosed with a lymphoproliferative disorder (such as lymphoma, CLL, or related conditions) - You have blood relatives who have also been diagnosed with similar conditions - You are willing to provide a blood or saliva sample and complete health questionnaires **You may NOT be eligible if...** - You do not have a qualifying diagnosis or family history - You are unable or unwilling to provide informed consent - You are not able to provide a biological sample Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Locations(1)

Mayo Clinic

Rochester, Minnesota, United States

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NCT00626496

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