RecruitingNCT00700414

International Pediatric Adrenocortical Tumor Registry


Sponsor

St. Jude Children's Research Hospital

Enrollment

9,999 participants

Start Date

Oct 1, 2001

Study Type

OBSERVATIONAL

Conditions

Summary

This study aims to collect demographic and medical information including detailed family history of cancer of children and adolescents with adrenocortical tumors in order to learn more about the clinical and epidemiological aspects, treatment modalities, and outcome of patients with this rare disease, worldwide. In addition, investigators at St. Jude Children's Research Hospital (SJCRH) plan to perform molecular studies of tumor cells aimed to clarify the role of the TP53 gene and other genetic pathways in these tumors. They aim to obtain relevant biological material from participants with adrenocortical tumor (ACT), their biological parents, and relatives for determination of the TP53 germline status, molecular studies of the TP53 gene, and other molecular pathways.


Eligibility

Max Age: 21 Years

Plain Language Summary

Simplified for easier understanding

This international registry collects data on children diagnosed with adrenocortical tumors (rare cancers or benign growths on the adrenal glands) to better understand these uncommon childhood tumors and improve treatment protocols worldwide. **You may be eligible if...** - Your child is under 18 years old and has been diagnosed with an adrenocortical tumor - You are willing to have your child's medical information and tumor samples entered into the international registry - You are receiving care at a participating institution **You may NOT be eligible if...** - Your child does not have a confirmed adrenocortical tumor - You are unable or unwilling to provide informed consent - Your child is not being treated at a participating center Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Locations(5)

Stanford University

Stanford, California, United States

All Children's Hospital/St. Petersburg Hospital

St. Petersburg, Florida, United States

The Children's Medical Center

Dayton, Ohio, United States

St. Jude Children's Research Hospital

Memphis, Tennessee, United States

Cook Children's Medical Center

Fort Worth, Texas, United States

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NCT00700414


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