RecruitingNCT00748254
Laser-based Photoacoustic Tomography of Human Inflammatory Arthritis
Sponsor
University of Michigan
Enrollment
113 participants
Start Date
Dec 1, 2011
Study Type
OBSERVATIONAL
Conditions
Summary
The purpose of this feasibility study is to determine if a new emerging technology called photoacoustic tomography (PAT) can be adapted for use in humans for the detection of chronic rheumatoid arthritis.
Eligibility
Min Age: 18 Years
Inclusion Criteria3
- Men and women 18 years of age or older can participate in this study.
- Patients can participate in this study if they have had rheumatoid arthritis for more than 2 years and their rheumatologist has referred them to this study.
- Patients can participate as a healthy volunteer with a known history of rheumatoid arthritis.
Exclusion Criteria7
- Patients, who have electrically, magnetically or mechanically activated implants such as heart pacemaker, magnetic surgical clips, prostheses or implanted neurological stimulator.
- Pregnant patients.
- Patients who is claustrophobic.
- Patients with impaired renal function cannot participate in this study such as elevate creatinine clearance, patients on kidney dialysis etc.
- Patients with shock hypotension or unstable low blood pressure.
- Patients with Rhabdomyolysis.
- Patients who have had a contrast enhanced (with gadolinium) MRA (magnetic resonance angiography)/ or MRI within the last 3 months. (Contrast is a medication injected into a vein during a imaging examination that helps produce clearer images/pictures).
Interventions
PROCEDURELaser Based Photoacoustic Tomography, MRI, Ultrasound
Healthy subjects will have scans on finger joints with any of the scanning methods described above.
PROCEDURElaser based photoacoustic tomography, MRI, ultrasound
Subjects with arthritis will have scans on finger joints with any of the scanning methods described above.
Locations(1)
View Full Details on ClinicalTrials.gov
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NCT00748254
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