Prostate Active Surveillance Study

This study is following men with low-risk prostate cancer who have chosen active surveillance (watching and waiting rather than immediate treatment) to understand whether this approach is safe and to track how the cancer changes over time. **You may be eligible if...** - You have been confirmed to have prostate cancer (adenocarcinoma) by biopsy - Your cancer appears to be confined to the prostate (no spread to lymph nodes or other organs) - You have not received any prior treatment for prostate cancer - You are in good physical health - You have chosen active surveillance as your management plan - Your cancer was diagnosed no more than 3 years ago - You have had no more than 2 prostate biopsies - Your biopsy had at least 10 core samples taken **You may NOT be eligible if...** - You are unwilling or unable to have regular prostate biopsies - You have a history of another cancer (except treated skin cancer, treated superficial bladder cancer, or other solid tumors with no evidence of disease for more than 5 years) Talk to your doctor to see if this trial is right for you.