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RecruitingPhase 4NCT00768820

The Psychiatric and Cognitive Phenotypes in Velocardiofacial Syndrome

The Psychiatric and Cognitive Phenotypes in Velocardiofacial Syndrome (VCFS), Williams Syndrome (WS)and Fragile X Syndrome Characterization, Treatment and Examining the Connection to Developmental and Molecular Factors

Sponsor

The Chaim Sheba Medical Center

Enrollment

400 participants

Start Date

May 1, 2001

Study Type

INTERVENTIONAL

Conditions

Williams SyndromeFragile X SyndromeVelocardiofacial Syndrome

Summary

The purpose of this study is to investigate the Psychiatric and Cognitive Phenotypes in Velocardiofacial Syndrome (VCFS), Williams Syndrome (WS)and Fragile X Syndrome Characterization, Treatment and Examining the Connection to Developmental and Molecular Factors

Eligibility

Plain Language Summary

Simplified for easier understanding

This study examines the psychiatric and cognitive features of Velocardiofacial Syndrome (VCFS), also known as 22q11.2 Deletion Syndrome. VCFS is a genetic condition associated with an increased risk of schizophrenia and other psychiatric disorders, as well as learning difficulties. Researchers want to better understand which specific brain changes and cognitive profiles are linked to mental health symptoms in this population. You may be eligible if: - You have a confirmed chromosomal deletion at the 22q11 region, proven by FISH (fluorescence in situ hybridization) genetic testing - There is no minimum or maximum age requirement You may NOT be eligible if: - There are no formal exclusion criteria listed Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DRUGmethylphenidate, fluoxetin, risperidone

first cognitive evaluation without methylphenidate,second cognitive evaluation with methylphenidate

Locations(1)

Schneider Children's Mediac Center of Israel

Petah Tikva, Israel

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NCT00768820

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