Mechanisms Underlying Impaired Diabetic Wound Healing

This study examines why wounds heal more slowly in people with diabetes compared to those without diabetes. By studying the biology of chronic wounds — wounds that have been present for more than 4 weeks — researchers aim to identify the specific biological mechanisms that impair healing and develop better treatments. You may be eligible if: - You are between 21 and 80 years old - You have a chronic wound that has been present for more than 4 weeks - You may have diabetes or not — both diabetic and non-diabetic patients are included - You are undergoing or have had adult surgical wound treatment You may NOT be eligible if: - You are unable to provide informed consent - You are pregnant - You are currently taking medications that significantly suppress your immune system - You are part of a vulnerable population as defined by federal research regulations (such as prisoners or certain institutionalized individuals) Talk to your doctor to see if this trial is right for you.