RecruitingNCT00882167

Cine-magnetic Resonance Imaging (MRI) Detecting Intra Abdominal Adhesions

Sensitivity and Predictive Value of Functional Cine Magnetic Resonance Imaging (MRI) Detecting Intra-abdominal Adhesions


Sponsor

Radboud University Medical Center

Enrollment

100 participants

Start Date

Apr 1, 2009

Study Type

OBSERVATIONAL

Conditions

Summary

Official title: Sensitivity and predictive value of functional cine magnetic resonance imaging (MRI) detecting intra-abdominal adhesions Background: Adhesions are a frequent problem in abdominal surgery. The formation of adhesions is part of a normal wound healing. However in some patients adhesions cause severe complications such as chronic pain, obstruction and strangulation of the bowel. Adhesions can also obstruct access to the peritoneal cavity and complicate reoperations. Accurate imaging of adhesions would be of benefit avoiding adhesion related complications at repeated laparotomy or laparoscopy. At present no validated diagnostic tool mapping adhesions exists. Purpose: To define the sensitivity and specificity of functional cineMRI in detecting and mapping adhesions in patients undergoing reoperation. Design: Prospective multicenter observational trial Primary outcome: Sensitivity and specificity of functional MRI detecting adhesions to the abdominal wall Secondary outcome: Sensitivity and specificity of functional MRI detecting organ-to-organ adhesions. Estimated enrollment: 100 Estimated study completion date: dec 2019 Estimated primary completion date: dec 2019


Eligibility

Min Age: 18 Years

Inclusion Criteria1

  • Patients with a median abdominal scar due to a previous open abdominal surgical procedures with a length of at least 10 cm and have given written consent.

Exclusion Criteria2

  • Severe claustrophobia.
  • No MRI allowed

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Interventions

OTHERCineMRI

CineMRI scan of the abdomen at 1.5 Tesla.


Locations(5)

Rijnstate Hospital

Arnhem, Gelderland, Netherlands

Radboud University Nijmegen Medical Center

Nijmegen, Gelderland, Netherlands

Jeroen Bosch Hospital

's-Hertogenbosch, Netherlands

Gelre Hospital

Apeldoorn, Netherlands

Catharina Hospital

Eindhoven, Netherlands

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NCT00882167