RecruitingNCT01050504

Collecting and Studying Blood and Tissue Samples From Patients With Locally Recurrent or Metastatic Prostate or Bladder/Urothelial Cancer

Molecular Correlates of Sensitivity and Resistance to Therapy in Genitourinary Malignancy

Sponsor

University of Washington

Enrollment

1,500 participants

Start Date

Aug 1, 2009

Study Type

OBSERVATIONAL

Conditions

Malignant Solid Neoplasm Recurrent Prostate Carcinoma Stage IV Bladder Cancer AJCC v7 Stage IV Prostate Cancer AJCC v7 Metastatic Malignant Neoplasm in the Bone Localized Renal Pelvis and Ureter Urothelial Carcinoma Metastatic Malignant Neoplasm in the Soft Tissues Metastatic Renal Pelvis and Ureter Urothelial Carcinoma Recurrent Bladder Carcinoma Recurrent Renal Pelvis and Ureter Urothelial Carcinoma Stage IV Bladder Urothelial Carcinoma AJCC v7

Summary

This study collects and studies tissue and blood samples from patients with prostate or bladder/urothelial cancer that has recurred (come back) at or near the same place as the original (primary) tumor or has spread to other parts of the body. Studying samples of blood and tissue samples from patients with prostate or bladder/urothelial cancer in the laboratory may help doctors learn more about new biomarkers, potential drug targets, and resistance developing in response to treatment. It may also help doctors find better ways to treat the cancer.

Eligibility

Sex: MALEMin Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study collects blood and tissue samples from patients with prostate or bladder cancer (and healthy volunteers) to study how these cancers develop and change, which may help develop better treatments in the future. **You may be eligible if...** - You have been diagnosed with prostate or bladder cancer (localized or spread to other parts of the body) - You are a healthy person without cancer who is having a standard urological procedure and agree to donate a small tissue sample - Your blood counts and clotting are within acceptable ranges **You may NOT be eligible if...** - You cannot stop blood thinners (warfarin or Lovenox) for at least 3 days before biopsy - You have an active serious infection - You received a VEGF-blocking drug (like Avastin/bevacizumab) in the last 28 days Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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