Pancreatic Cancer Genetics
Molecular Genetics and Epidemiology of Pancreatic Cancer in Ashkenazi Jewish Patients
Columbia University
100 participants
Jan 1, 2008
OBSERVATIONAL
Conditions
Summary
The aim of this study is to determine the frequency of the three most common BReast CAncer gene 1 (BRCA1) and BReast CAncer gene 2 (BRCA2) genetic mutations that are commonly found in Ashkenazi Jewish patients with pancreatic cancer. Testing for BRCA1 and BRCA2 mutations in relatives of hereditary pancreatic cancer patients may have a significant impact; allowing for early screening, treatment, and resection of pre-malignant tissue or malignant lesions.
Eligibility
Inclusion Criteria3
- Patients diagnosed with pancreatic cancer.
- Patients are of Ashkenazi Jewish descent.
- Patients have been Columbia Pancreatic Cancer Prevention Program Registry and Tissue Bank for High-Risk Individuals (IRB-AAAA6154).
Exclusion Criteria2
- Inability to provide informed consent.
- Under the age of 18 years old.
Locations(1)
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NCT01102569