RecruitingNCT01102569

Pancreatic Cancer Genetics

Molecular Genetics and Epidemiology of Pancreatic Cancer in Ashkenazi Jewish Patients

Sponsor

Columbia University

Enrollment

100 participants

Start Date

Jan 1, 2008

Study Type

OBSERVATIONAL

Conditions

Pancreatic Cancer

Summary

The aim of this study is to determine the frequency of the three most common BReast CAncer gene 1 (BRCA1) and BReast CAncer gene 2 (BRCA2) genetic mutations that are commonly found in Ashkenazi Jewish patients with pancreatic cancer. Testing for BRCA1 and BRCA2 mutations in relatives of hereditary pancreatic cancer patients may have a significant impact; allowing for early screening, treatment, and resection of pre-malignant tissue or malignant lesions.

Eligibility

Min Age: 18 YearsMax Age: 85 Years

Plain Language Summary

Simplified for easier understanding

This study looks at the genetic factors underlying pancreatic cancer specifically in patients of Ashkenazi Jewish descent, to identify inherited gene changes that may increase cancer risk. **You may be eligible if...** - You have been diagnosed with pancreatic cancer - You are of Ashkenazi Jewish descent - You are already enrolled in the Columbia Pancreatic Cancer Prevention Program Registry **You may NOT be eligible if...** - You are unable to provide informed consent - You are under 18 years old Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

Interested in this trial?

Get notified about updates and connect with the research team.

Locations(1)

Columbia University Medical Center

New York, New York, United States

View Full Details on ClinicalTrials.gov

For the most up-to-date information, visit the official listing.

Visit

NCT01102569

Related Trials

DESTINY-PANTUMOUR04

NCT0712400017 locations

Study of Daraxonrasib (RMC-6236) in Patients With Resected Pancreatic Ductal Adenocarcinoma (PDAC)

NCT0725223217 locations

Incremental Value of Magnetic Resonance Imaging in Selection of Pancreatic Cancer Patients for Surgery

NCT054283583 locations

In-Depth Characterisation of Biliary Strictures and Hepato-Pancreato-Biliary Focal Lesions for Development of New Technologies to Tackle Hepato-Pancreato-Biliary Cancers

NCT072063551 location

Adapted Guided Stereotactic Body Radiotherapy Combined With Chemotherapy and Enhancement of Novel Drug Ivonescimab for Pancreatic Cancer (ASCEND)

NCT068444221 location