RecruitingNCT01102569

Pancreatic Cancer Genetics

Molecular Genetics and Epidemiology of Pancreatic Cancer in Ashkenazi Jewish Patients


Sponsor

Columbia University

Enrollment

100 participants

Start Date

Jan 1, 2008

Study Type

OBSERVATIONAL

Conditions

Summary

The aim of this study is to determine the frequency of the three most common BReast CAncer gene 1 (BRCA1) and BReast CAncer gene 2 (BRCA2) genetic mutations that are commonly found in Ashkenazi Jewish patients with pancreatic cancer. Testing for BRCA1 and BRCA2 mutations in relatives of hereditary pancreatic cancer patients may have a significant impact; allowing for early screening, treatment, and resection of pre-malignant tissue or malignant lesions.


Eligibility

Min Age: 18 YearsMax Age: 85 Years

Inclusion Criteria3

  • Patients diagnosed with pancreatic cancer.
  • Patients are of Ashkenazi Jewish descent.
  • Patients have been Columbia Pancreatic Cancer Prevention Program Registry and Tissue Bank for High-Risk Individuals (IRB-AAAA6154).

Exclusion Criteria2

  • Inability to provide informed consent.
  • Under the age of 18 years old.

Locations(1)

Columbia University Medical Center

New York, New York, United States

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NCT01102569


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