Molecular Analysis of Samples From Patients With Diffuse Intrinsic Pontine Glioma and Brainstem Glioma

This study collects and analyzes tumor samples from patients with brainstem gliomas (brain tumors located in the brainstem) to understand the molecular makeup of these cancers and find better treatment targets. **You may be eligible if...** - You have been diagnosed with diffuse intrinsic pontine glioma (DIPG), a type of brainstem tumor, at any age - You have another type of high-grade (aggressive) glioma originating in the brainstem - You have a low-grade (slower-growing) focal glioma of the brainstem **You may NOT be eligible if...** - Your brain tumor started outside the brainstem (even if it spread there) - You have a brainstem tumor of a different cell type (e.g., primitive neuroectodermal tumor) Talk to your doctor to see if this trial is right for you.