Pharmacokinetics of Posaconazole in Allogeneic Transplant Patients With Mucositis

This study looks at how the antifungal drug posaconazole is absorbed by the body in patients who have recently had an allogeneic (donor) stem cell transplant and are experiencing mucositis — painful inflammation and ulcers in the mouth and digestive tract. Mucositis may affect how well the drug is absorbed, and this study aims to find the right dosing approach. You may be eligible if: - You are 18 to 75 years of age - You are receiving an allogeneic stem cell transplant - You are being prescribed posaconazole (oral suspension or tablet) to prevent fungal infections You may NOT be eligible if: - You have gastroparesis (a condition where your stomach empties too slowly) - You have vomiting or diarrhea within 2 hours of taking posaconazole - You are taking enzyme-inducing medications such as carbamazepine, phenytoin, phenobarbital, rifampicin, or similar drugs - You are under 18 years of age Talk to your doctor to see if this trial is right for you.