RecruitingNCT01429389

Specimen Collection from Pregnant Women At Increased Risk for Fetal Aneuploidy

Collection of Whole Blood Specimens from Pregnant Women At Increased Risk of Fetal Chromosomal Abnormality for Use in Development of a Noninvasive Prenatal Test in the Detection of the Relative Quantity of Chromosomal Material in Circulating Cell-Free DNA Extracted from Maternal Plasma


Sponsor

Sequenom, Inc.

Enrollment

2,000 participants

Start Date

May 1, 2011

Study Type

OBSERVATIONAL

Conditions

Summary

The specimen collection is designed for the purpose of the development of a noninvasive prenatal test for T21.


Eligibility

Sex: FEMALEMin Age: 18 Years

Inclusion Criteria6

  • pregnant between 10 and 22 weeks gestation
  • years of age or older
  • provides signed and dated informed consent
  • subject is at increased risk for fetal aneuploidy
  • subject is willing to undergo a CVS and/or amniocentesis procedure for the purpose of genetic analysis
  • subject agrees to provide the genetic results of the invasive procedure

Exclusion Criteria2

  • Fetal demise at time of specimen sampling
  • Previous sample donation under this protocol

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Locations(14)

University of Alabama Birmingham

Birmingham, Alabama, United States

Cedars-Sinai Medical Center

Los Angeles, California, United States

Sharp-Rees Stealy Medical Group

San Diego, California, United States

UCSD

San Diego, California, United States

Women's Health Care Research

San Diego, California, United States

Specialty Obstetrics of San Diego

San Diego, California, United States

Reproductive Genetics Institute

Chicago, Illinois, United States

University of Iowa Health Care

Iowa City, Iowa, United States

Henry Ford Hospital

Detroit, Michigan, United States

Spectrum Health

Grand Rapids, Michigan, United States

The Cooper Health System

Camden, New Jersey, United States

Medical University of South Carolina

Charleston, South Carolina, United States

IWK Health Centre

Halifax, Nova Scotia, Canada

North York General Hospital

Toronto, Ontario, Canada

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NCT01429389


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