RecruitingNot ApplicableNCT01558544

Cryopreservation of Ovarian Tissue

Cryopreservation of Ovarian Tissue for Potential In Vitro Maturation or Autologous Transplantation

Sponsor

Weill Medical College of Cornell University

Enrollment

300 participants

Start Date

Apr 1, 1997

Study Type

INTERVENTIONAL

Conditions

Cancer Fertility Preservation Risk of Premature Ovarian Failure

Summary

The study hopes to contribute to the development of technologies of ovarian tissue freezing-thawing and in vitro maturation of immature eggs such that a person at risk for premature ovarian failure might be able to conceive a genetically related child.

Eligibility

Sex: FEMALEMax Age: 45 Years

Inclusion Criteria8

Females 0-45 years of age who are premenopausal
Treatment plan that will likely result in premature menopause or premature ovarian failure
This includes patients receiving:
Cancer treatment with abdominal pelvic irradiation and/or high dose chemotherapy
Surgery that requires removal of ovaries for medical condition or disease, e.g. Prophylactic oophorectomy in BRCA patients
Patient is unable or unwilling to pursue fertility preservation by freezing oocytes or embryos.
Previous treatment for cancer is acceptable if patient still has ovarian function
Patient is medically stable enough to undergo surgery (cleared for anesthesia)

Exclusion Criteria3

Patients not meeting the above criteria
Patients who have not received medical clearance from their physicians to undergo surgery
Patients already experiencing menopause.