RecruitingNCT01840293

Breast Cancer Proteomics and Molecular Heterogeneity


Sponsor

Cancer Trials Ireland

Enrollment

1,780 participants

Start Date

Feb 1, 2013

Study Type

OBSERVATIONAL

Conditions

Summary

Primary objective: The primary objective is to define the proteomic and molecular characteristics of primary and recurrent/ metastatic breast tumours with special focus on the expression of S100 protein and the estrogen receptor (ER), progesterone receptor (PR) and epidermal growth factor receptor 2 (HER2) genes Secondary objective: * To expand our understanding of the complex molecular pathways dictating the progression of breast cancer and their response to different treatment regimes. * To relate proteomic findings to survival data * To identify potential serum markers of breast cancer progression


Eligibility

Sex: FEMALEMin Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study collects tumor tissue and blood samples from people with breast cancer — whether newly diagnosed, recurrent, or metastatic (spread) — to study the molecular diversity of breast tumors and identify patterns that predict treatment response. **You may be eligible if...** - You are 18 or older and have been diagnosed with primary breast cancer, recurrent breast cancer, or newly diagnosed stage 4 (metastatic) breast cancer - You are scheduled for surgery or a biopsy to remove or sample tumor tissue - You are able to provide informed consent **You may NOT be eligible if...** - There are no additional specific exclusion criteria listed beyond being unable to give consent Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

Interested in this trial?

Get notified about updates and connect with the research team.


Locations(6)

Cork University Hospital

Cork, Ireland

Beaumont Hospital

Dublin, Ireland

St James's Hospital

Dublin, Ireland

St. Vincent's University Hospital

Dublin, Ireland

University Hospital Limerick

Limerick, Ireland

University Hospital Waterford

Waterford, Ireland

View Full Details on ClinicalTrials.gov

For the most up-to-date information, visit the official listing.

Visit

NCT01840293