RecruitingNot ApplicableNCT02016248

SBRT Boost for Unfavorable Prostate Cancer'

Prospective Evaluation of Stereotactic Body Radiotherapy Boost for Unfavorable Localized Prostate Cancer


Sponsor

MemorialCare Health System

Enrollment

150 participants

Start Date

Jun 1, 2012

Study Type

INTERVENTIONAL

Conditions

Summary

The purpose of this study is to find out whether giving a short course of focused radiation called an SBRT "boost" is a safe and effective way to treat prostate cancer. This boost delivers a high dose of radiation to the prostate in a non-invasive way, similar to what is done with high dose rate (HDR) brachytherapy but without using needles. The study looks at how well this treatment controls the cancer, what side effects it may cause, and how it affects patients' quality of life over time.


Eligibility

Sex: MALEMin Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study is testing whether adding a focused radiation treatment called stereotactic body radiation therapy (SBRT) as a targeted boost to the prostate — on top of standard radiation — can improve outcomes for men with higher-risk prostate cancer while limiting side effects. **You may be eligible if...** - You have been diagnosed with prostate cancer classified as intermediate or high risk (based on PSA level, Gleason score, and tumor stage) - You are scheduled to receive radiation therapy for your prostate cancer - You are in generally good health and your urinary function is adequate before treatment - You are at least 18 years old **You may NOT be eligible if...** - You have had prior radiation to the pelvis - You have had previous prostate surgery - You have serious urinary problems that would be worsened by radiation - You have cancer that has spread beyond the prostate to lymph nodes or distant organs - You are unable to lie still for the radiation treatment sessions Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

RADIATIONStereotactic body radiotherapy (SBRT) Boost

The intervention in this study is the SBRT boost, which is a short course of five high-dose stereotactic body radiotherapy treatments (5.5 Gy × 5 fractions, total 27.5 Gy) delivered with image-guided precision to the prostate. This SBRT boost is given in addition to standard external-beam radiation therapy (EBRT), which delivers 50.4 Gy to the pelvis, prostate, and proximal seminal vesicles.


Locations(3)

Orange Coast Memorial Medical Center

Fountain Valley, California, United States

Saddleback Memorial Medical Center

Laguna Hills, California, United States

Long Beach Memorial Medical Center

Long Beach, California, United States

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NCT02016248


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