RecruitingNCT02055105

Modulation of Molecular Fingerprinting in Pediatric Sepsis


Sponsor

Phoenix Children's Hospital

Enrollment

50 participants

Start Date

Mar 1, 2014

Study Type

OBSERVATIONAL

Conditions

Summary

The goal of this study is to demonstrate the sensitivity and specificity of detecting circulating micro RNA (miRNA) biomarkers in pediatric septic patients. It will also follow expression and modulation of levels in response to therapy in comparison to current biomarkers.


Eligibility

Min Age: 1 YearMax Age: 18 Years

Inclusion Criteria4

  • Age 1 through 18 years
  • Patients admitted to the PICU with concerns for sepsis or those developing sepsis during their admission to the hospital.
  • Patients must be enrolled int he study from arrival time tot he ED up to 24 hours from the time of initiation of antibiotic therapy for treatment of sepsis or septic shock.
  • Signed informed consent.

Exclusion Criteria1

  • Patients <1 year of age and greater than 18 years of age.

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Interventions

PROCEDUREmiRNA in Sepsis

miRNA in Sepsis


Locations(2)

Phoenix Children's Hospital

Phoenix, Arizona, United States

Phoenix Children's Hospital

Phoenix, Arizona, United States

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NCT02055105


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