RecruitingNCT02087852

Kidney Cancer DNA Registry


Sponsor

Memorial Sloan Kettering Cancer Center

Enrollment

750 participants

Start Date

Mar 1, 2014

Study Type

OBSERVATIONAL

Conditions

Summary

This registry will help us develop better methods of: * Preventing these cancers * Diagnosing these cancers * Treating these cancers


Eligibility

Min Age: 18 Years

Inclusion Criteria13

  • Kidney Cancer Case Cohort:
  • Must be ≥ 18 years of age AND
  • Must be an English-speaker AND
  • Must have a diagnosis or suspicion of kidney cancer
  • Family Member Cohort:
  • Must be ≥ 18 years of age AND
  • Must be an English-speaker AND
  • Must be a blood relative of the proband. Family members of probands including mother, father, sisters, brothers, half-sisters, half-brothers, daughters, sons, grandmothers, grandfathers, as well as aunts and uncles are eligible. These individuals need not have kidney cancer, as they will be used for segregation analysis of suspected variants found in the proband; requesting DNA from relatives is required.
  • Control Cohort:
  • Must be ≥ 18 years of age AND
  • Must be an English-speaker AND
  • Must not have a personal history of cancer, with the exception of nonmelanoma skin cancer, AND
  • Must not be a blood relative of any cases or controls enrolled in this study

Exclusion Criteria1

  • Patients who, in the opinion of the primary MSKCC clinician or the investigator, have a condition that precludes their ability to provide an informed consent

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Interventions

OTHERsalvia for germline DNA
BEHAVIORALthe Kidney Cancer Questionnaire

Patients will complete the appropriate surveys on either paper or on the computer/iPad in the office using REDCap software. If patients are unable to complete their questionnaires at the time of their in-office visit, a link to the questionnaires in REDCap will be emailed to them. The survey data that is collected in REDCap will be stored in REDCap. Clinic staff may also call patients to remind patients to complete questionnaires.

BEHAVIORALFamily History Questionnaire (when applicable)

Patients will complete the appropriate surveys on either paper or on the computer/iPad in the office using REDCap software. If patients are unable to complete their questionnaires at the time of their in-office visit, a link to the questionnaires in REDCap will be emailed to them. The survey data that is collected in REDCap will be stored in REDCap. Clinic staff may also call patients to remind patients to complete questionnaires.

OTHERBlood draw
BEHAVIORALEpidemiologic Questionnaire

Patients will complete the appropriate surveys on either paper or on the computer/iPad in the office using REDCap software. If patients are unable to complete their questionnaires at the time of their in-office visit, a link to the questionnaires in REDCap will be emailed to them. The survey data that is collected in REDCap will be stored in REDCap. Clinic staff may also call patients to remind patients to complete questionnaires.


Locations(7)

Memorial Sloan Kettering at Basking Ridge (Consent and Follow-up)

Basking Ridge, New Jersey, United States

Memorial Sloan Kettering Monmouth (Consent and Follow up)

Middletown, New Jersey, United States

Memorial Sloan Kettering Bergen (Consent and Follow up )

Montvale, New Jersey, United States

Memorial Sloan Kettering Commack (Consent and Follow-up)

Commack, New York, United States

Memorial Sloan Kettering Westchester (Consent and Follow up)

Harrison, New York, United States

Memorial Sloan Kettering Cancer Center (All Protocol Activities)

New York, New York, United States

Memorial Sloan Kettering Nassau (Consent and Follow-Up)

Uniondale, New York, United States

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NCT02087852


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