RecruitingNot ApplicableNCT02095808

Metabolic Biomarkers in Thoracic Cancers


Sponsor

University of Texas Southwestern Medical Center

Enrollment

200 participants

Start Date

Mar 20, 2013

Study Type

INTERVENTIONAL

Conditions

Summary

The purpose of this research study is to develop a method of using magnetic resonance imaging (MRI) to evaluate lung tumors and other thoracic malignancies. An MRI is a scanning device that uses magnets to make images (pictures) of the body. This study is being done to determine what series of reactions (metabolic pathways) pulmonary nodules use as they burn sugar as fuel for growth. The manner in which the tumor burns (metabolizes) sugar for fuel is being investigated by using a natural, slightly modified, sugar solution (13C-glucose) and studying a small sample of the tumor once it is removed at the time of surgery.


Eligibility

Min Age: 18 Years

Inclusion Criteria2

  • Patients must have known or probable malignant lesions requiring surgical biopsy or excision.
  • Subjects of all races and ethnic origins over 18 years of age.

Exclusion Criteria2

  • Not a surgical candidate.
  • Poorly controlled diabetes.

Interventions

PROCEDUREImaging Biomarkers

Want to see if using 13C-glucose helps in detecting cancer and deciding on a treatment plan.


Locations(1)

University of Texas Southwestern Medical Center

Dallas, Texas, United States

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NCT02095808


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