RecruitingNot ApplicableNCT02095808

Metabolic Biomarkers in Thoracic Cancers


Sponsor

University of Texas Southwestern Medical Center

Enrollment

200 participants

Start Date

Mar 20, 2013

Study Type

INTERVENTIONAL

Conditions

Summary

The purpose of this research study is to develop a method of using magnetic resonance imaging (MRI) to evaluate lung tumors and other thoracic malignancies. An MRI is a scanning device that uses magnets to make images (pictures) of the body. This study is being done to determine what series of reactions (metabolic pathways) pulmonary nodules use as they burn sugar as fuel for growth. The manner in which the tumor burns (metabolizes) sugar for fuel is being investigated by using a natural, slightly modified, sugar solution (13C-glucose) and studying a small sample of the tumor once it is removed at the time of surgery.


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study is examining biological markers (called metabolic biomarkers) found in blood and tissue samples from patients with thoracic cancers — cancers of the chest area, including lung cancer, cancers of the windpipe, and chest wall tumors. The goal is to better understand the underlying biology of these cancers, identify patterns that distinguish different cancer types, and potentially uncover new ways to predict outcomes or guide more targeted treatments in the future. **You may be eligible if...** - You are 18 or older, of any race or ethnic background - You have a known or suspected cancerous tumor in the chest area that requires surgery - Your care plan already includes a surgical biopsy or surgical removal of the tumor as part of your standard treatment **You may NOT be eligible if...** - You are not a surgical candidate — meaning surgery is considered medically unsafe or inappropriate for you - You have diabetes that is poorly controlled and not being effectively managed with medication Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

PROCEDUREImaging Biomarkers

Want to see if using 13C-glucose helps in detecting cancer and deciding on a treatment plan.


Locations(1)

University of Texas Southwestern Medical Center

Dallas, Texas, United States

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NCT02095808


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