RecruitingPhase 2NCT02127398

Stool Transplants to Treat Refractory Clostridium Difficile Colitis

Fecal Microbiota Transplantation in Refractory Clostridium Difficile Colitis


Sponsor

Duke University

Enrollment

77 participants

Start Date

Apr 1, 2016

Study Type

INTERVENTIONAL

Conditions

Summary

It has been shown that restoration of the normal makeup of the bowel bacterial population is the most effective way to treat recurrent colitis due to Clostridium difficile. Restoration of the normal bowel bacterial population is best done by transplanting stool from a healthy donor. The investigators wish to transplant stool from healthy donors to treat recurrent C. difficile colitis by incorporating the stool into capsules that are administered by the oral route.


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a biological treatment called fecal microbiota for people with clostridium difficile colitis. The study is currently recruiting participants at 1 location. People eligible for this study include aged 18 Years and older.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

BIOLOGICALfecal microbiota

fecal microbiota in capsule form


Locations(1)

Duke University Medical Center

Durham, North Carolina, United States

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NCT02127398