RecruitingNCT02253030

OCT Angiography in Wet AMD

Optical Coherence Tomography Angiography in Neovascular Age-related Macular Degeneration


Sponsor

Oregon Health and Science University

Enrollment

160 participants

Start Date

Sep 1, 2014

Study Type

OBSERVATIONAL

Conditions

Summary

The primary goals of this study are to use optical coherence tomography (OCT) angiography (blood vessel mapping) to: 1. diagnose the presence of new blood vessels in wet age-related macular degeneration (AMD) 2. evaluate patients undergoing treatment for wet AMD 3. determine if reduced flow to the choroid is a risk factor for developing wet AMD.


Eligibility

Min Age: 50 YearsMax Age: 100 Years

Inclusion Criteria5

  • Adults aged 50 and older with clinical findings of treatment-naïve (never treated) neovascular AMD with active new blood vessel growth confirmed by clinical testing will be considered
  • No evidence of retinal disease
  • Refractive error greater than +3.00 diopters or -7.00 diopters (glasses Rx)
  • No recent eye surgery in the last 4 months
  • No significant cataract to interfere with the quality of the imaging

Exclusion Criteria6

  • Inability to give informed consent
  • Significant kidney disease
  • Blood pressure greater than 180/110
  • Previous macular laser treatment
  • Inability to maintain stable fixation during OCT imaging
  • Visual acuity worse than 20/200

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Interventions

DEVICEOptical Coherence Tomography

Locations(1)

Casey Eye Institute, Oregon Health & Science University

Portland, Oregon, United States

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NCT02253030