RecruitingNCT02296307

DOvEE - Diagnosing Ovarian & Endometrial Cancer Early

Diagnosing Ovarian & Endometrial Cancer Early (DOvEE) by Targeting Symptomatic Women


Sponsor

McGill University

Enrollment

13,600 participants

Start Date

Jan 1, 2012

Study Type

OBSERVATIONAL

Conditions

Summary

This study hopes to improve early detection of ovarian and endometrial cancers. It will determine if women with bloating, abdominal distension, abdominal/pelvic pain, increased urinary frequency and/or early satiety, benefit from earlier surgery after screening by CA-125 ovarian cancer biomarker and transvaginal ultrasound.


Eligibility

Sex: FEMALEMin Age: 45 Years

Plain Language Summary

Simplified for easier understanding

This trial is studying whether women who have symptoms like bloating, pelvic pain, or changes in bowel habits may have early-stage ovarian or endometrial (uterine) cancer, using a special test on cells collected from inside the womb. **You may be eligible if...** - You are 45 years of age or older - You have had at least one of the listed symptoms (such as bloating, early fullness when eating, pelvic discomfort, or unusual vaginal bleeding) for at least 2 weeks but less than 1 year - You are able to give informed consent **You may NOT be eligible if...** - You are under 45 years of age - You have no qualifying symptoms - You have already been diagnosed with gynecologic cancer Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

OTHERBlood test: CA-125 biomarker

* CA-125 biomarker blood test at visit 1, day 1. * CA-125 biomarker blood test at visit 2, week 6.

OTHERSecond Test: Transvaginal Ultrasound

-Transvaginal Ultrasound at visit 1, day 1.

OTHERFollow-up phone call

Phone call 6 months after last visit to verify continued health.


Locations(8)

West Island Cancer Wellness Centre

Kirkland, Quebec, Canada

Axion 50 plus

Laval, Quebec, Canada

Clinique Familiale Pas-A-Pas

Montreal, Quebec, Canada

Clinique Médicale du Haut-Anjou

Montreal, Quebec, Canada

McGill University Health Centre, Royal Victoria Hospital

Montreal, Quebec, Canada

Queen Elizabeth Health Centre

Montreal, Quebec, Canada

Lachine Hospital

Montreal, Quebec, Canada

Clinique du Dr. L. Quintal

Saint-Lambert, Quebec, Canada

View Full Details on ClinicalTrials.gov

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NCT02296307


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