RecruitingNCT02300766

Cerebellar Mutism Syndrome Study

Nordic Study of the Cerebellar Mutism Syndrome in Children With Brain Tumours of the Posterior Fossa

Sponsor

Rigshospitalet, Denmark

Enrollment

1,000 participants

Start Date

Oct 1, 2014

Study Type

OBSERVATIONAL

Conditions

Infratentorial Neoplasms Mutism

Summary

The purpose of this study is to determine why up to 25% of the pediatric patients who have surgery for a tumor in the posterior fossa develops the Cerebellar Mutism Syndrome (CMS). Furthermore the purpose is to explore the clinical course and the best treatment of the syndrome.

Eligibility

Max Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This trial is studying a condition called cerebellar mutism syndrome — where children temporarily lose the ability to speak after brain tumor surgery — to better understand why it happens and how to prevent or treat it. **You may be eligible if...** - Your child is under 18 years old - Their imaging showed a tumor in the back part of the brain (cerebellum, 4th ventricle, or brainstem) - They are scheduled for or have had surgery (resection or biopsy) for this tumor — including second or further surgeries - A parent or guardian has given informed consent **You may NOT be eligible if...** - There are no stated exclusion criteria — all eligible patients may enroll Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Locations(30)

Medical University of Vienna

Vienna, Austria

University Hospital Leuven

Leuven, Belgium

Motol University Hospital

Prague, Czechia

Aalborg University Hospital

Aalborg, Denmark

Aarhus University Hospital

Aarhus, Denmark

Rigshospitalet

Copenhagen, Denmark

Odense University Hospital

Odense, Denmark

Helsinki University Central Hospital

Helsinki, Finland

Kuopio University Hospital

Kuopio, Finland

Oulu University Hospital

Oulu, Finland

Tampere University Hospital

Tampere, Finland

Turku University Hospital

Turku, Finland

University of Leipzig Medical Center

Leipzig, Germany

Semmelweis University, 2nd Dept of Pediatrics

Budapest, Hungary

Ospedale Pediatrico Bambino Gesù

Rome, Italy

Hospital of Lithuanian University of Health Sciences Kauno klinikos

Kaunas, Lithuania

Radboud University Nijmegen Medical Centre

Nijmegen, Gelderland, Netherlands

UMC Groningen

Groningen, Netherlands

UMC Utrecht

Utrecht, Netherlands

Haukeland University Hospital

Bergen, Norway

Oslo University Hospital

Oslo, Norway

University Hospital of North Norway

Tromsø, Norway

St. Olav's Hospital

Trondheim, Norway

Sahlgrenska University Hospital

Gothenburg, Sweden

Linköping University Hospital

Linköping, Sweden

Skåne University Hospital

Skåne, Sweden

Karolinska University Hospital

Stockholm, Sweden

University Hospital of Umeå

Umeå, Sweden

Uppsala University Hospital

Uppsala, Sweden

Alder Hey Childrens NHS Foundation Trust

Liverpool, United Kingdom

View Full Details on ClinicalTrials.gov

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NCT02300766