RecruitingNCT02300766

Cerebellar Mutism Syndrome Study

Nordic Study of the Cerebellar Mutism Syndrome in Children With Brain Tumours of the Posterior Fossa


Sponsor

Rigshospitalet, Denmark

Enrollment

1,000 participants

Start Date

Oct 1, 2014

Study Type

OBSERVATIONAL

Conditions

Summary

The purpose of this study is to determine why up to 25% of the pediatric patients who have surgery for a tumor in the posterior fossa develops the Cerebellar Mutism Syndrome (CMS). Furthermore the purpose is to explore the clinical course and the best treatment of the syndrome.


Eligibility

Max Age: 18 Years

Inclusion Criteria3

  • Age \< 18 years at the date of first imaging showing this tumour
  • Tumour in the cerebellum/4th ventricle/brainstem with intention to treat with surgical resection or open biopsy. Second and further surgeries are also included.
  • Informed consent from custodial parent(s)

Exclusion Criteria1

  • None

Locations(30)

Medical University of Vienna

Vienna, Austria

University Hospital Leuven

Leuven, Belgium

Motol University Hospital

Prague, Czechia

Aalborg University Hospital

Aalborg, Denmark

Aarhus University Hospital

Aarhus, Denmark

Rigshospitalet

Copenhagen, Denmark

Odense University Hospital

Odense, Denmark

Helsinki University Central Hospital

Helsinki, Finland

Kuopio University Hospital

Kuopio, Finland

Oulu University Hospital

Oulu, Finland

Tampere University Hospital

Tampere, Finland

Turku University Hospital

Turku, Finland

University of Leipzig Medical Center

Leipzig, Germany

Semmelweis University, 2nd Dept of Pediatrics

Budapest, Hungary

Ospedale Pediatrico Bambino Gesù

Rome, Italy

Hospital of Lithuanian University of Health Sciences Kauno klinikos

Kaunas, Lithuania

Radboud University Nijmegen Medical Centre

Nijmegen, Gelderland, Netherlands

UMC Groningen

Groningen, Netherlands

UMC Utrecht

Utrecht, Netherlands

Haukeland University Hospital

Bergen, Norway

Oslo University Hospital

Oslo, Norway

University Hospital of North Norway

Tromsø, Norway

St. Olav's Hospital

Trondheim, Norway

Sahlgrenska University Hospital

Gothenburg, Sweden

Linköping University Hospital

Linköping, Sweden

Skåne University Hospital

Skåne, Sweden

Karolinska University Hospital

Stockholm, Sweden

University Hospital of Umeå

Umeå, Sweden

Uppsala University Hospital

Uppsala, Sweden

Alder Hey Childrens NHS Foundation Trust

Liverpool, United Kingdom

View Full Details on ClinicalTrials.gov

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NCT02300766