Leuven Tolerogenic Protocol for Intestinal Transplantation

This observational study is following patients who have received intestinal transplants under a specialized immunological protocol (the Leuven Tolerogenic Protocol) designed to help the immune system accept the transplanted bowel without high-dose immunosuppression. The protocol involves a donor blood transfusion before transplant, low-dose steroids and anti-rejection drugs, and careful surgical techniques to reduce inflammation and preserve gut lining integrity. You may be eligible if you are awaiting intestinal transplantation at the participating center; living donor transplants are excluded from this cohort. Participation involves consenting to blood sample collection and data recording during your clinical follow-up visits after transplant. This summary was prepared using AI to help patients understand this research.