International Pachyonychia Congenita Research Registry

This trial is maintaining an international patient registry for people diagnosed with pachyonychia congenita (PC) — a rare genetic condition that typically causes severely thickened and painful nails, calluses on the soles of the feet, cysts, and in some cases mouth sores or hoarse voice. The registry collects data to help researchers understand how the disease varies between patients, track outcomes, and develop potential treatments for this uncommon condition. **You may be eligible if...** - You have been clinically diagnosed with pachyonychia congenita or a similar related disorder affecting your nails, skin, or mucous membranes - You are willing to share your health information and participate in the registry **You may NOT be eligible if...** - There are no stated exclusion criteria for this registry — anyone with a qualifying diagnosis may enroll regardless of age or location Talk to your doctor to see if this trial is right for you.