18F-FSPG PET in Imaging Patients With Liver Cancer Before Undergoing Surgery or Transplant

This study is testing a new type of imaging scan called an 18F-FSPG PET scan to see if it can better detect and diagnose liver tumors before patients undergo surgery or other treatments. **You may be eligible if...** - You are 18 years of age or older - You have been diagnosed with liver cancer (hepatocellular carcinoma), a benign liver tumor, another type of liver tumor (such as bile duct cancer or cancer that has spread from the colon or pancreas), or cancer that has spread to a limited number of sites in the body - You have already had standard imaging (MRI or CT scan) as part of your care - You are being considered for surgery, liver transplant, or a radiation-based treatment for your liver tumor **You may NOT be eligible if...** - You are under 18 years old - You have liver cancer but are not a candidate for surgery, transplant, or radiation treatment - You are pregnant or breastfeeding - You have poorly controlled diabetes (fasting blood sugar over 200 mg/dL) - You have a specific aggressive type of liver cancer called the infiltrative variant Talk to your doctor to see if this trial is right for you.