RecruitingNot ApplicableNCT02389673

Intra-operative Radiotherapy For Women With Ductal Carcinoma in Situ Breast Cancer

Intra-operative Radiotherapy After Breast-conversing Surgery in Treating Women With Ductal Carcinoma in Situ Breast Cancer

Sponsor

Liao Ning

Enrollment

222 participants

Start Date

Oct 1, 2014

Study Type

INTERVENTIONAL

Conditions

Breast Neoplasms

Summary

Whether the patients with low grade ductal carcinoma in situ breast cancer should accept radiationtherapy is uncertain.Radiation therapy uses high-energy x-rays to damage tumor cells. Giving radiation during surgery followed by external-beam radiation to the entire breast may kill more tumor cells.The clinical trial is conducting to find out the effectiveness of radiation therapy during surgery in treating women who have undergone breast-conversing surgery for low grade ductal carcinoma in situ breast cancer.

Eligibility

Sex: FEMALEMin Age: 18 YearsMax Age: 70 Years

Plain Language Summary

Simplified for easier understanding

This study is testing whether targeted radiation delivered directly during surgery (called intraoperative radiotherapy) is effective and safe for women with a low-grade, early-stage type of breast condition called ductal carcinoma in situ (DCIS) — abnormal cells found inside the milk ducts that have not yet spread. **You may be eligible if...** - You have low-grade DCIS - Your tumor is smaller than 5 cm - You are a candidate for breast-conserving surgery (lumpectomy) - You have already had a lumpectomy with clear or nearly clear margins - You are currently having re-excision of the surgical area and/or lymph node evaluation - There is no sign the cancer has spread to other parts of the body **You may NOT be eligible if...** - Your tumor is larger than 5 cm - You have intermediate or high-grade DCIS - You have invasive breast cancer - There is no medical indication for a radiation boost Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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