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RecruitingNot ApplicableNCT02445885

Late Reperfusion With Percutaneous Coronary Intervention in Patients With ST-segment Elevation Myocardial Infarction

Sponsor

Thomas Engstrom

Enrollment

150 participants

Start Date

May 1, 2015

Study Type

INTERVENTIONAL

Conditions

Ischemic Heart Disease

Summary

Although recommended therapy for patients with ST-segment elevation myocardial infarction is primary PCI, it remains unestablished whether patients with a symptom duration of more 12 hours benefit from acute revascularisation. This study aims to investigate whether acute intervention is superior to subacute intervention in these patients.

Eligibility

Min Age: 18 Years

Inclusion Criteria3

  • Patients more than 18 years of age.
  • STEMI \> 12 hours and \< 36 hours.
  • Clinical stable, i.e. no on going angina, hemodynamically stable (systolic BP \> 90) and Killip class \< 3.

Exclusion Criteria10

  • Clinical instability which requires an acute invasive strategy.
  • Left main occlusion or multivessel disease which requires CABG.
  • Previous Q-wave infarction in the current infarct related artery.
  • Left Bundle Branch Block (LBBB).
  • Severe renal insufficiency.
  • Pacemaker
  • Chronic atrial fibrillation.
  • Previous Coronary Artery Bypass Surgery (CABG).
  • Pregnancy.
  • Other severe illness with life expectancy less than 1 year
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Interventions

PROCEDUREPCI

Guideline directed Percutaneous Coronary Intervention

Locations(1)

Rigshospitalet

Copenhagen, Capital Region, Denmark

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NCT02445885

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