RecruitingNot ApplicableNCT02455193

Neuronal Effects of Exercise in Schizophrenia


Sponsor

University of Colorado, Denver

Enrollment

140 participants

Start Date

Aug 1, 2014

Study Type

INTERVENTIONAL

Conditions

Summary

This study plans to learn more about how common drugs prescribed to individuals with schizophrenia contribute to weight gain, as well as how exercise and diet impact appetite and the brain's response to food. In this study, the investigators will be evaluating how participants' brains respond to food images as well as asking questions about their food preferences and intake and clinical symptoms. The investigators may also ask participants to complete an exercise or diet intervention to see how this changes brain responses or food preferences.


Eligibility

Min Age: 21 YearsMax Age: 70 Years

Inclusion Criteria4

  • Diagnosis of schizophrenia or schizoaffective disorder
  • Between 21 and 70 years of age
  • Currently prescribed either olanzapine, risperidone, clozapine, or haloperidol, OR not currently being treated with any neuroleptic medications
  • Weight stable within 5 percent for the last 6 months

Exclusion Criteria3

  • Pregnancy
  • Substance abuse
  • Significant endocrine/metabolic disease (e.g., uncontrolled hypertension, severe hypertriglyceridemia)

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Interventions

BEHAVIORALExercise
BEHAVIORALDiet

Locations(1)

University of Colorado Anschutz Medical Campus

Aurora, Colorado, United States

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NCT02455193


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