RecruitingNot ApplicableNCT02535936

Cortical Plasticity in Spastic Diplegia After Selective Dorsal Rhizotomy


Sponsor

The University of Texas Health Science Center, Houston

Enrollment

15 participants

Start Date

Aug 1, 2015

Study Type

INTERVENTIONAL

Conditions

Summary

The purpose of this study is to characterize the cortical connectivity changes in the brain of spastic diplegic children after Selective Dorsal Rhizotomy.


Eligibility

Min Age: 3 YearsMax Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study examines brain plasticity (how the brain reorganizes itself) in children with spastic diplegia — a form of cerebral palsy affecting both legs — before and after they undergo Selective Dorsal Rhizotomy (SDR), a surgery that cuts nerve roots to reduce muscle spasticity. You may be eligible if: - Your child has been diagnosed with spastic diplegia (cerebral palsy affecting both legs) - Your child is scheduled for or has had Selective Dorsal Rhizotomy surgery - Your child is between 3 and 18 years old You may NOT be eligible if: - Your child is not having Selective Dorsal Rhizotomy surgery Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

PROCEDURE3Tesla MRI with DTI-MRI and rsfcMRI under general anesthesia

2 post-operative MRI's at 2 months and 12 months


Locations(1)

UTHealth & Children's Memorial Hermann Hospital

Houston, Texas, United States

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NCT02535936


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