RecruitingPhase 3NCT02638389

Efficacy and Safety of Sirolimus in Vascular Anomalies That Are Refractory to Standard Care

Phase III Multicentric Study Evaluating the Efficacy and Safety of Sirolimus in Vascular Anomalies That Are Refractory to Standard Care


Sponsor

Cliniques universitaires Saint-Luc- Université Catholique de Louvain

Enrollment

250 participants

Start Date

Jan 25, 2016

Study Type

INTERVENTIONAL

Conditions

Summary

The phosphatidylinositol 3-kinase (PI3Kinase)/Protein Kinase B (AKT)/mammalian target of rapamycin (mTor) pathway plays a role on the development and the venous/lymphatic vascular organisations. The investigators want to study the efficacy and the safety of Rapamycin, an mTor inhibitor.


Eligibility

Min Age: 3 MonthsMax Age: 70 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a drug called Sirolimus for people with vascular malformations. The study is currently recruiting participants at 3 locations.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DRUGSirolimus

evaluate the efficacy and safety of sirolimus in these patients


Locations(3)

Cliniques Universitaires Saint-Luc, Université Catholique de Louvain Bruxelles

Brussels, Brussels Capital, Belgium

CHU Caen

Caen, Brittany Region, France

Universitätsklinikum Freiburg

Freiburg im Breisgau, Germany

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NCT02638389


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