RecruitingNCT02670447

Early Identification of Patients Presenting a First Psychotic Episode, Non Answering to First Line Support Strategies

Early Identification of Patients Presenting a First Psychotic Episode, Non Answering to First Line Support Strategies: A Multicentric Study


Sponsor

Centre Hospitalier Universitaire de Saint Etienne

Enrollment

80 participants

Start Date

Dec 11, 2025

Study Type

OBSERVATIONAL

Conditions

Summary

Researchers propose in this project to evaluate predictive factors of non response. It is defined by the lack of symptomatic remission at month 3, for patients presenting a first episode of psychosis. It will be performed on objective markers taken from imagery techniques. The link between evolution of these markers and clinical measures will be studied.


Eligibility

Min Age: 18 YearsMax Age: 35 Years

Plain Language Summary

Simplified for easier understanding

This study is looking at people experiencing their first episode of psychosis (a break from reality, including hallucinations or delusions) to identify early signs and understand what factors influence long-term outcomes, with the goal of improving early detection and treatment. **You may be eligible if...** - You are experiencing or have recently experienced your first episode of psychosis - You are between the ages specified by the study (typically 15–40 years) - You are willing to participate in interviews, questionnaires, and follow-up assessments - You have not had a previous diagnosis of a psychotic disorder **You may NOT be eligible if...** - Your psychosis is caused by substance use or a known medical condition (such as a brain tumor or infection) - You have been previously diagnosed with a psychotic disorder - You are unable to provide informed consent - You have a serious physical illness that would confound the study results Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

PROCEDUREMRI

Magnetic Resonance Imagery will be performed on patients attempted by schizophrenia. The aim of this intervention is an early detection of the non-answering patients to the primary cares.


Locations(5)

Chu Le Vinatier

Bron, France

Chu Clermont-Ferrand

Clermont-Ferrand, France

Chu Grenoble

Grenoble, France

HÔPITAL Edouard Herriot

Lyon, France

Chu Saint Etienne

Saint-Etienne, France

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NCT02670447


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