High Volume Washing of the Abdomen in Increasing Survival After Surgery in Patients With Pancreatic Cancer That Can Be Removed by Surgery

This study is testing whether washing the abdominal cavity with large amounts of fluid during pancreatic cancer surgery (called extensive lavage) can reduce the spread of cancer cells and improve survival rates after the operation. **You may be eligible if...** - You are 18 years or older - Your doctors have recommended surgery to remove part or all of your pancreas - Your doctors suspect you have pancreatic cancer or a cancer near the pancreas (periampullary cancer) - Your surgeon believes you are healthy enough to undergo the procedure - You are willing to be randomly assigned to different types of lavage techniques during surgery **You may NOT be eligible if...** - You do not have a surgical recommendation for pancreatic surgery - Your surgeon believes surgery would be too risky for you medically - You are under 18 years old - You are not willing to be randomly assigned to a treatment group Talk to your doctor to see if this trial is right for you.