Evaluation Of The Lung Microbiome In NTM Bronchiectasis

This study is examining the bacteria living in the lungs of people with bronchiectasis (a condition where the airways are permanently widened and scarred) linked to a type of bacteria called NTM (nontuberculous mycobacteria), to understand how the lung's bacterial community may affect the disease. **You may be eligible if...** - You have lung symptoms such as a persistent cough, fatigue, fever, shortness of breath, unexplained weight loss, or coughing up blood - You have abnormal findings on a chest scan, including bronchiectasis or small lung nodules - You have tested positive for NTM bacteria from at least two sputum samples or one lung wash (bronchoscopy) — OR you have similar symptoms but negative NTM tests (as a comparison group) **You may NOT be eligible if...** - Your symptoms are caused by a different lung condition (not NTM-related bronchiectasis) - You cannot provide sputum samples or undergo bronchoscopy - You are unwilling to give informed consent Talk to your doctor to see if this trial is right for you.