Comparison of Proton and Photon Radiotherapy of Brain Tumors (ProtoChoice-Hirn)

This study is comparing two types of radiation therapy — proton therapy (a newer, more targeted type) and standard photon X-ray radiation — for people with brain tumors, to see which approach is better in terms of effectiveness and side effects. **You may be eligible if...** - You have a primary brain tumor such as a glioma, meningioma, pituitary adenoma, craniopharyngioma, or other rare brain tumor - Or you have a brain tumor that has come back, either with or without prior radiation treatment - Your tumor requires radiation therapy, possibly combined with chemotherapy - Both proton and standard radiation are medically appropriate options for your situation - You are 18 years or older and well enough to be treated as an outpatient - You are able to understand and sign a consent form **You may NOT be eligible if...** - You are unable to give informed consent - There is already a clearly preferred radiation type established as the standard for your specific tumor Talk to your doctor to see if this trial is right for you.