Tumor Cell and DNA Detection in the Blood, Urine and Bone Marrow of Patients With Solid Cancers

This study is investigating whether cancer cells and cancer DNA shed from tumors can be detected in the blood, urine, and bone marrow of patients with various solid cancers, which could eventually lead to better and less invasive ways to detect and monitor cancer. **You may be eligible if...** - You are over 18 years old - You have been diagnosed with a solid cancer such as lung, esophagus, stomach, bile duct or pancreas, colorectal, melanoma, or sarcoma at any stage - You are scheduled for surgery related to your cancer - You are of any gender or ethnicity **You may NOT be eligible if...** - You are not scheduled for surgical treatment - You have a blood cancer such as leukemia or lymphoma rather than a solid tumor Note: A small group of people without cancer who are having surgery for a non-cancerous reason may also be enrolled as a comparison group. Talk to your doctor to see if this trial is right for you.