RecruitingPhase 4NCT02845531

Implantable Cardioverter Defibrillator Versus Optimal Medical Therapy In Patients With Variant Angina Manifesting as Aborted Sudden Cardiac Death

Sponsor

Kee-joon Choi

Enrollment

140 participants

Start Date

Nov 29, 2016

Study Type

INTERVENTIONAL

Conditions

Sudden Cardiac Death Angina Pectoris, Variant

Summary

The purpose of this study is to determine whether ICD(Implantable Cardioverter Defibrillator) implantation on the top of optimal medical therapy in patients with variant angina manifesting as aborted sudden cardiac death reduces the incidence of the death from any cause compared with optimal medical therapy alone.

Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study is comparing two treatments for patients who survived a sudden cardiac arrest caused by variant angina — a condition where the heart's arteries suddenly spasm and temporarily cut off blood flow — to see whether an implantable defibrillator or medications alone provide better protection. **You may be eligible if...** - You are 18 or older - You survived a cardiac arrest caused by a confirmed dangerous heart rhythm (ventricular fibrillation or very rapid ventricular tachycardia) - Your cardiac arrest was caused by coronary artery spasm, confirmed by heart imaging with or without a spasm-provocation test **You may NOT be eligible if...** - You have a significant blockage (more than 50%) in a coronary artery - Your heart pumps less than 35% of its normal capacity - You have structural heart problems such as a scarred or abnormally thickened heart muscle - You have chronic heart failure Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DEVICEImplantable Cardioverter Defibrillator

Implantable Cardioverter Defibrillator and Optimal Medical Therapy

DRUGOptimal Medical Therapy

Locations(25)

Soon Chun Hyang University Hospital Bucheon

Bucheon-si, South Korea

Busan National University Yangsan Hospital

Busan, South Korea

Busan University Hospital

Busan, South Korea

Dong-A Medical Center

Busan, South Korea

Soon Chun Hyang University Hospital Cheonan

Cheonan, South Korea

Keimyung University Dongsan Medical Center

Daegu, South Korea

Chungnam National University Hospital

Daejeon, South Korea

Gangneung Asan Hospital

Gangneung, South Korea

Chonnam National University Hospital

Gwangju, South Korea

Wonkwang University Hospital

Iksan, South Korea

Gachon University Gil Medical Center

Incheon, South Korea

Chonbuk National University Hospital

Jeonju, South Korea

Chungnam National University Sejong Hospital

Sejong, South Korea

Seoul university Bundang hospital

Seongnam, South Korea

Asan Medical Center

Seoul, South Korea

Ewha Womans University Mokdong Hospital

Seoul, South Korea

Kangdong KyungHee University hospital

Seoul, South Korea

Korea University Anam Hospital

Seoul, South Korea

Korea University Guro Hospital

Seoul, South Korea

Seoul National University Boramae Medical Center

Seoul, South Korea

Seoul National University Hospital

Seoul, South Korea

Severance Hospital

Seoul, South Korea

The Catholic Univ. of Korea, Seoul St. Mary's Hospital

Seoul, South Korea

The Catholic University of Korea, Eunpyeong St. Mary's Hospital

Seoul, South Korea

Ajou University Hospital

Suwon, South Korea

View Full Details on ClinicalTrials.gov

For the most up-to-date information, visit the official listing.

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NCT02845531

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