Comparison of Hepatectomy and Local Ablation for Resectable Synchronous and Metachronous Colorectal Liver Metastasis

This study compares two treatments for colorectal cancer (bowel cancer) that has spread to the liver: surgical removal of the liver tumors (hepatectomy) versus destroying the tumors using heat or cold (ablation), to determine which is more effective. **You may be eligible if...** - You have colorectal cancer (colon or rectal cancer) confirmed by biopsy - Your cancer has spread to the liver (liver metastases), also confirmed by biopsy - You do not have cancer spread to other organs - You are healthy enough for surgery or ablation **You may NOT be eligible if...** - Your cancer has spread to places other than the liver that cannot all be fully treated - You have active complications like a bowel blockage or internal bleeding - You are not healthy enough to safely undergo surgery or anesthesia Finding the best way to treat liver metastases from bowel cancer could significantly improve survival. Talk to your doctor to see if this trial is right for you.