RecruitingNCT02886247

Pancreatic Cancer Registry: For Any Person With a Personal or Family History

National Familial Pancreas Tumor Registry

Sponsor

Johns Hopkins University

Enrollment

12,000 participants

Start Date

Jun 1, 1994

Study Type

OBSERVATIONAL

Conditions

Pancreatic Cancer, ATM, BRCA, Hereditary Cancer

Summary

The NFPTR was established in 1994 to find the causes of pancreatic cancer. In brief, the investigators are interested in both the genetic and non-genetic causes of pancreatic cancer. The investigators are particularly interested in finding the genes that cause pancreatic cancer to cluster in some families. Up to 10% of pancreatic cancer patients have another close relative who has also developed pancreatic cancer. This clustering of pancreatic cancers in families has yet to be explained; however, the investigators continue to identify new familial pancreatic cancer genes that explain this clustering in subsets of families. For example, in 2009 and 2012 the investigators discovered that mutations in the PALB2 and ATM genes jointly account up to 5% of the clustering of pancreatic cancer in families.

Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This registry collects information from people with a personal or family history of pancreatic tumors, to help researchers understand who is at risk and develop better early detection and prevention strategies. **You may be eligible if...** - You have a personal history of pancreatic tumors (you were diagnosed with a tumor of the pancreas yourself) - Or you have a family history of pancreatic tumors (a close relative was diagnosed) **You may NOT be eligible if...** - There are no specific exclusion criteria listed — the registry is open to anyone with a personal or family connection to pancreatic tumors By joining this registry, you help researchers learn who is most at risk for pancreatic cancer, which could lead to earlier detection and better outcomes. Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Locations(1)

Johns Hopkins Hospital

Baltimore, Maryland, United States

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NCT02886247