RecruitingNot ApplicableNCT02920554

The Effect in Wedge Resection and IVb/V Resection of the Liver for Gallbladder Cancer

The Effect in Wedge Resection and IVb/V Resection of the Liver for Gallbladder Cancer Operation: Prospective Randomized Controlled Trial

Sponsor

Saint Vincent's Hospital, Korea

Enrollment

88 participants

Start Date

Jul 1, 2014

Study Type

INTERVENTIONAL

Conditions

Gallbladder Cancer

Summary

The extent of hepatic resection for gallbladder cancer can be done from a wedge resection to 4b/5 bisegmentectomy. This study aims to compare the recurrence rates and survival rates between wedge resection group and bisegmentectomy group. Patients with T2 or T3 gallbladder cancer on preoperative CT exam or patients who were pathologically diagnosed as T2 or T3 gallbladder cancer after initial simple cholecystectomy were enrolled. All patients are randomly assigned to wedge resection or bisegmentectomy group. Number of patients in each group is 44. Primary endpoint is recurrence-free-survival rates and overall survival rates.

Eligibility

Min Age: 19 YearsMax Age: 80 Years

Plain Language Summary

Simplified for easier understanding

This study compares two surgical techniques for treating gallbladder cancer that has grown into nearby tissue (T2 or T3 stage): removing just a wedge of liver tissue around the gallbladder versus a more extensive liver segment removal, to find out which results in better outcomes. **You may be eligible if...** - You have been diagnosed with T2 or T3 gallbladder cancer (cancer that has grown into surrounding tissue but not spread distantly) on scans - Or you were found to have T2 or T3 cancer after an initial gallbladder removal operation **You may NOT be eligible if...** - Your cancer has spread to the lining of the abdomen (peritoneal seeding) or to distant organs - The cancer cannot be fully removed surgically - Your cancer is a rare non-standard type (like sarcoma or adenosquamous carcinoma) - The initial surgery left cancer cells behind (R1 or R2 resection) Understanding the best surgical approach for gallbladder cancer can improve survival rates for this difficult-to-treat cancer. Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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