RecruitingNCT02927158

Exome and Genome Analysis to Elucidate Genetic Etiologies and Population Characteristics in the Plain Community

Use of Whole Exome Sequencing/Whole Genome Sequencing in the Plain Communities


Sponsor

University of Pittsburgh

Enrollment

300 participants

Start Date

Aug 1, 2016

Study Type

OBSERVATIONAL

Conditions

Summary

This study is designed to utilize whole exome and whole genome sequencing techniques to identify underlying genetic causes for undiagnosed disorders in the Plain Communities, and to do population genetic studies looking at genetic drift and founder mutations in this unique population.


Eligibility

Max Age: 100 Years

Inclusion Criteria1

  • Any person of Amish or Mennonite descent

Exclusion Criteria1

  • Individuals who are not of Amish or Mennonite descent

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Locations(1)

Children's Hospital of Pittsburgh of UPMC

Pittsburgh, Pennsylvania, United States

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NCT02927158


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