RecruitingNot ApplicableNCT02958462

Pre-myeloid Cancer and Bone Marrow Failure Clinic Study

Sponsor

Mayo Clinic

Enrollment

2,000 participants

Start Date

Jan 16, 2017

Study Type

INTERVENTIONAL

Conditions

Hematopoietic and Lymphatic System Neoplasm Hematologic Neoplasms Myeloid Malignancy Clonal Cytopenia of Undetermined Significance Clonal Hematopoiesis of Indeterminate Potential Cytopenia Inherited Bone Marrow Failure Syndrome Idiopathic Cytopenia of Undetermined Significance Bone Marrow Failure Syndrome Clonal Expansion Hereditary Neoplastic Syndrome Idiopathic Dysplasia of Uncertain Significance Low Risk Myelodysplastic Syndrome

Summary

This clinical trial tests next generation sequencing (NGS) for the detection of precursor features of pre-myeloid cancers and bone marrow failure syndromes. NGS is a procedure that looks at relevant cancer associated genes and what they do. Finding genetic markers for pre-malignant conditions may help identify patients who are at risk of pre-myeloid cancers and bone marrow failure syndromes and lead to earlier intervention.

Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a procedure called Biospecimen Collection, a procedure called Bone Marrow Biopsy, and others for people with bone marrow failure syndrome, clonal cytopenia of undetermined significance, and other related conditions. The study is currently recruiting participants at 3 locations. People eligible for this study include aged 18 Years and older.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

PROCEDUREBiospecimen Collection

Undergo blood sample, hair follicle, and saliva collection

PROCEDUREBone Marrow Biopsy

Undergo a bone marrow biopsy

PROCEDUREPunch Biopsy

Undergo a skin punch biopsy

PROCEDUREBuccal Swab

Undergo a saliva or buccal swab

OTHERClinical Evaluation

Undergo clinical assessment

OTHERGenetic Counseling

Receive genetic counseling

OTHERQuality-of-Life Assessment

Ancillary studies

OTHERElectronic Health Record Review

Ancillary studies

Locations(3)

Mayo Clinic in Arizona

Scottsdale, Arizona, United States

Mayo Clinic in Florida

Jacksonville, Florida, United States

Mayo Clinic in Rochester

Rochester, Minnesota, United States

View Full Details on ClinicalTrials.gov

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NCT02958462

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