Antimicrobial Prophylaxis for Skin Colonization With Propionibacterium Acnes in Primary Open Shoulder Surgery
Antimicrobial Prophylaxis for Skin Colonization With Propionibacterium Acnes in Primary Open Shoulder Surgery: A Double Blinded Randomized Controlled Trial
Université de Montréal
88 participants
Dec 1, 2016
INTERVENTIONAL
Conditions
Summary
INESS Antibiotic Prophylaxis in Orthopedic Guide recommends the use of Cefazolin at induction for all orthopaedic procedure with implantation of internal fixation device. With the increasing rate of identified P. acnes shoulder surgery infection despite the use of recommended skin preparation and preoperative prophylactic antibiotics, a question arises; Is Cefazolin the most effective prophylactic antibiotic for shoulder surgery? The objective of this study is to determine if Ceftriaxone is superior to Cefazolin as a prophylactic antibiotic for skin colonization with P. acnes in primary shoulder surgery
Eligibility
Inclusion Criteria3
- years and older
- Male or female
- Presenting normal skin on the shoulder aria
Exclusion Criteria7
- Used antibiotics or treated their skin with antibiotic gel, alcohol gel or cream or acne treatment in the last three months
- Active infection at the surgical site or anywhere
- Affected shoulder previously received radiotherapy
- Allergic to one of the antimicrobial prophylaxis used
- Open fracture
- Life threatening or a limb threatening pathology
- Liver or kidney failure
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Interventions
Antibiotic that will be give before a Trauma or elective open shoulder surgery
Antibiotic that will be give before a Trauma or elective open shoulder surgery
Locations(1)
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NCT02996656