RecruitingNot ApplicableNCT02998229

The Artisse™ Intrasaccular Device is Indicated for the Treatment of Wide-neck Bifurcating Intracranial Aneurysms (IAs).

Artisse™ Intrasaccular Device IDE


Sponsor

Medtronic Neurovascular Clinical Affairs

Enrollment

300 participants

Start Date

Apr 16, 2024

Study Type

INTERVENTIONAL

Conditions

Summary

The purpose of this study is to assess the safety and effectiveness of the Artisse™ Intrasaccular Device in the treatment of unruptured and ruptured wide-neck bifurcating intracranial aneurysms.


Eligibility

Min Age: 18 YearsMax Age: 75 Years

Plain Language Summary

Simplified for easier understanding

This study evaluates the Artisse intrasaccular device — a small implant placed inside a brain aneurysm to block blood flow and prevent rupture — for the treatment of wide-neck bifurcation aneurysms (balloon-like bulges at forks in brain arteries). The goal is to confirm its safety and effectiveness in real-world use. You may be eligible if: - You are between 18 and 75 years old - You have a single brain aneurysm (ruptured or unruptured) requiring treatment - The aneurysm is saccular (balloon-shaped), located at a bifurcation, and has a wide neck - If ruptured, you are neurologically stable (Hunt and Hess Grade I or II) - You have one or more risk factors for aneurysm rupture You may NOT be eligible if: - Your aneurysm was previously treated with coils or stents - You have an active bacterial infection - You are pregnant or plan to become pregnant within 1 year of the procedure - You have kidney failure (unless on dialysis) - You have a life expectancy of less than 5 years from a separate illness - You are on anticoagulants that cannot be stopped Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DEVICEArtisse™ Intrasaccular Device

Intrasaccular Device


Locations(22)

Swedish Medical Center

Englewood, Colorado, United States

Yale New Haven Hospital

New Haven, Connecticut, United States

Baptist Medical Center Jacksonville

Jacksonville, Florida, United States

Tampa General Hospital

Tampa, Florida, United States

University of Chicago

Chicago, Illinois, United States

Advocate Lutheran General Hospital

Park Ridge, Illinois, United States

University of Iowa Hospitals and Clinics

Iowa City, Iowa, United States

Massachusetts General Hospital

Boston, Massachusetts, United States

Cooper University Health

Camden, New Jersey, United States

Albany Medical Center

Albany, New York, United States

Buffalo General Medical Center

Buffalo, New York, United States

The Mount Sinai Hospital

New York, New York, United States

Stony Brook University Hospital

Stony Brook, New York, United States

Novant Health Brain and Spine Surgery

Charlotte, North Carolina, United States

Cleveland Clinic Foundation

Cleveland, Ohio, United States

Hospital of the University of Pennsylvania

Philadelphia, Pennsylvania, United States

Thomas Jefferson University Hospital

Philadelphia, Pennsylvania, United States

UPMC Presbyterian

Pittsburgh, Pennsylvania, United States

Prisma Health

Greenville, South Carolina, United States

Semmes Murphy Clinic

Memphis, Tennessee, United States

University of Utah Hospital

Salt Lake City, Utah, United States

West Virginia University

Morgantown, West Virginia, United States

View Full Details on ClinicalTrials.gov

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NCT02998229


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