RecruitingNCT03002272

Transcatheter Aortic Prosthesis Function: A Long-term Follow-up Study


Sponsor

Medstar Health Research Institute

Enrollment

100 participants

Start Date

Feb 20, 2018

Study Type

OBSERVATIONAL

Summary

In this observational study, the investigators will enroll subjects who underwent TAVR or SAVR more than 3 years ago. Clinical and procedural data from the implant/surgery will be collected, alongside clinical and echocardiographic data from subsequent follow-up visits.


Eligibility

Min Age: 18 Years

Inclusion Criteria3

  • a) TAVR performed more than 3 years ago
  • SAVR performed more than 3 years ago
  • Propensity matched to an enrolled TAVR subject

Exclusion Criteria4

  • Subjects unable to consent to participate, unless the subject has a legally authorized representative
  • Subjects unwilling to participate
  • Subject has undergone re-intervention to prosthetic aortic valve since TAVR procedure (e.g. balloon valvuloplasty, SAVR, re-do TAVR, paravalvular leak closure)
  • Echocardiographic evidence of prosthetic valve dysfunction within first 3 years post-TAVR (mean aortic gradient ≥20mmHg AND/OR moderate-severe transvalvular aortic regurgitation)

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Interventions

DEVICETAVR

subjects that underwent TAVR more than 3 years ago

DEVICESAVR

Historical controls will be selected from among patients at the same site who underwent isolated bioprosthetic SAVR more than 3 years ago


Locations(1)

Washington Hospital Center

Washington D.C., District of Columbia, United States

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NCT03002272