RecruitingNCT03010150

Blood Tests and Questionnaires in Studying Adherence to Preventative Swallowing Exercises in Participants With Metastatic Head and Neck Cancer

Modeling Adherence to Preventive Swallowing Exercises in Head and Neck Cancer

Sponsor

M.D. Anderson Cancer Center

Enrollment

471 participants

Start Date

Dec 29, 2016

Study Type

OBSERVATIONAL

Conditions

Summary

This trial uses blood tests and questionnaires to study how well participants with head and neck cancer that has spread to other places in the body adhere to swallowing exercises to prevent future disease. Using blood tests to study cytokines (proteins related to the immune system) may help doctors learn if certain levels of cytokines affect whether or not side effects occur and if they put participants at risk for future disease. Questionnaires may help doctors learn about the reasons head and neck cancer participants may or may not follow the swallowing exercises that they are asked to perform after receiving radiation treatments.

Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study is looking at how well patients with head and neck cancer stick to their prescribed swallowing exercises during radiation treatment, and whether blood markers or questionnaires can predict who will keep up with the exercises and who will struggle. **You may be eligible if...** - You are scheduled to receive radiation therapy with the goal of curing your cancer of the mouth, throat, voice box, or an unknown primary (cancer found in neck lymph nodes with no known primary site) - Your cancer is at stage II through IVB (non-HPV related throat cancer) - You have HPV-related throat cancer that meets specific stage criteria (T1 with lymph node involvement, or T2 or higher with no distant spread) - Your cancer is in the voice box or lower throat at stage II or higher **You may NOT be eligible if...** - You have already completed radiation treatment - You have cancer that has spread to distant organs - You are unable to participate in swallowing exercise protocols Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

PROCEDUREBiospecimen Collection

Provide blood samples

OTHERQuestionnaire Administration

Ancillary studies

Locations(1)

M D Anderson Cancer Center

Houston, Texas, United States

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NCT03010150

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