Two Therapeutic Strategies in First-line in Patients With Epithelial Advanced Ovarian Cancer

This trial compares two different treatment strategies for women with advanced ovarian cancer (stage III or IV) to find out which approach leads to better outcomes after surgery. **You may be eligible if...** - You are between 18 and 74 years old - You have been diagnosed with advanced ovarian, fallopian tube, or primary peritoneal cancer (stage III or IV) confirmed by a tissue biopsy - You have recently had surgery (within 3 weeks) to remove as much of the cancer as possible, or are about to start chemotherapy before surgery - Your blood counts and kidney function are within acceptable ranges **You may NOT be eligible if...** - Your cancer has spread outside the abdomen to distant organs (except lymph nodes or the lining of the lungs) - You have received chemotherapy for ovarian cancer previously - Your heart's pumping function (ejection fraction) is below 50% - You have had another invasive cancer within the past 5 years - You are pregnant or breastfeeding - You have known allergies to the study drugs Talk to your doctor to see if this trial is right for you.