RecruitingNCT03030755

Corneal Elastography and Patient Specific Modeling


Sponsor

The Cleveland Clinic

Enrollment

60 participants

Start Date

May 1, 2016

Study Type

OBSERVATIONAL

Conditions

Summary

The goal of this research is to develop measurement tools and simulation technology for characterizing and predicting individual responses to corneal treatments and for advancing understanding of corneal ectasia risk factors. Patients who either 1) have keratoconus and are being evaluated for corneal crosslinking or 2) have refractive error and are being evaluated for refractive surgery procedures such as LASIK will have their eyes imaged to assess their mechanical properties and will have computational simulations performed to predict the response to treatment. One aim of the study is to test the hypothesis that computational models can predict the cornea's shape changes within clinically acceptable limits of error.


Eligibility

Min Age: 16 YearsMax Age: 80 Years

Inclusion Criteria2

  • Any patient with keratoconus diagnosed by standard criteria, including topographic steepness, irregular astigmatism with a pattern consistent with keratoconus.
  • Any patient deemed a candidate for LASIK (laser vision correction) and scheduled for surgery.

Exclusion Criteria1

  • Inability to provide informed consent, including non-English speaking (if interpreter not available) and cognitively/mentally impaired (if legal guardian not available).

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Interventions

OTHEROptical coherence tomography

Locations(1)

Cleveland Clinic Foundation Cole Eye Institute

Cleveland, Ohio, United States

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NCT03030755