RecruitingNCT03030755

Corneal Elastography and Patient Specific Modeling


Sponsor

The Cleveland Clinic

Enrollment

60 participants

Start Date

May 1, 2016

Study Type

OBSERVATIONAL

Conditions

Summary

The goal of this research is to develop measurement tools and simulation technology for characterizing and predicting individual responses to corneal treatments and for advancing understanding of corneal ectasia risk factors. Patients who either 1) have keratoconus and are being evaluated for corneal crosslinking or 2) have refractive error and are being evaluated for refractive surgery procedures such as LASIK will have their eyes imaged to assess their mechanical properties and will have computational simulations performed to predict the response to treatment. One aim of the study is to test the hypothesis that computational models can predict the cornea's shape changes within clinically acceptable limits of error.


Eligibility

Min Age: 16 YearsMax Age: 80 Years

Plain Language Summary

Simplified for easier understanding

This study uses a specialized ultrasound technique called elastography to measure the stiffness of the cornea (the clear front surface of the eye) in patients with keratoconus (a condition where the cornea thins and bulges) and in patients undergoing LASIK laser eye surgery. The goal is to improve surgical planning and predict outcomes using patient-specific computer models. You may be eligible if: - You are between 16 and 80 years of age - You have been diagnosed with keratoconus, OR you are scheduled to undergo LASIK laser vision correction You may NOT be eligible if: - You are unable to provide informed consent (e.g., non-English speaker without an interpreter, or cognitive impairment without a legal guardian) Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

OTHEROptical coherence tomography

Locations(1)

Cleveland Clinic Foundation Cole Eye Institute

Cleveland, Ohio, United States

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NCT03030755


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