Molecular and Immunohistochemical Profiling of Tumors in Patients With Parathyroid Tumors

This study examines tumor tissue and blood samples from patients with parathyroid tumors (glands near the thyroid that control calcium levels) to identify the genetic and molecular changes driving these tumors, including both cancerous and non-cancerous types. **You may be eligible if...** - You have been diagnosed with overactive parathyroid glands (primary hyperparathyroidism) and have had surgery or treatment at MD Anderson Cancer Center or a partner institution - Your tumor has been classified as parathyroid cancer, an unusual (atypical) parathyroid growth, or a parathyroid adenoma (non-cancerous tumor) - You previously gave consent for your tissue or blood to be used for research - There are no restrictions on age, gender, or ethnicity **You may NOT be eligible if...** - No tissue or blood sample from your case is available for analysis Talk to your doctor to see if this trial is right for you.