RecruitingNot ApplicableNCT03059043

Safety and Efficacy Study of A Viscoelastic-free Method for Implantable Collamer Lens (ICL) Implantation

Prospective, Multicenter,Randomized Clinical Investigation of A Viscoelastic-free Method for Implantable Collamer Lens (ICL) Implantation to Treat High Myopia: A Pilot Study


Sponsor

Wenzhou Medical University

Enrollment

60 participants

Start Date

Nov 16, 2018

Study Type

INTERVENTIONAL

Conditions

Summary

This study evaluates the safety and efficacy of a viscoelastic-free method for Implantable Collamer Lens(ICL) implantation to treat high myopia. The subjects undergo randomization of ICL implantation using the viscoelastic-free method on one eye and undergoing standard method on the other one. The post-operative data are collected for analysis.


Eligibility

Min Age: 18 YearsMax Age: 45 Years

Inclusion Criteria8

  • Documented stable refraction for at least 1 year(within 0.5D)
  • Best spectacle-corrected visual acuity (BCVA) of 20/40 or better
  • Clear central cornea
  • 5D to -18.0D of myopic refractive error
  • Normal anterior chamber depth at least 2.8 mm to endothelium
  • Endothelial cell density (ECD) more than 2000 cell/mm2
  • Pupil diameter smaller than 7.0 mm under mesopic condition
  • Discontinued 3 weeks for hard contact lens and 1 week for soft contact lens wear

Exclusion Criteria4

  • Preexisting ocular diseases or conditions other than myopia, evidence of progressive or acute ocular disease
  • Evidence of connective tissue disease or other systemic diseases that may confound the results of the study;
  • Narrow angle of anterior chamber
  • Pregnant, lactating, or planning to become pregnant during the course of the trial

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Interventions

DEVICEviscoelastic-free implantation system

Viscoelastic-free implantation system use balanced salt solution irrigation during the implantation

DEVICEstandard viscoelastic-assisted Implantation system

This method utilize the viscoelastic agent to fill and maintain the anterior chamber during the implantation


Locations(5)

Guangdong General Hospital

Guangzhou, Guangdong, China

Hunan Provincial People's Hospital

Changsha, Hunan, China

The Eye Hispital of Wenzhou Medical University

Wenzhou, Zhejiang, China

Peking Union Medical College Hospital

Beijing, China

Shanghai Ninth People's Hospital

Shanghai, China

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NCT03059043


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