RecruitingNCT03097952

"Real-life" Cohort Study on Patients With Chronic HBV Infection in Jiangsu

"Real-life" Cohort Study on Patients With Chronic Hepatitis B Virus Infection in Jiangsu


Sponsor

The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School

Enrollment

20,000 participants

Start Date

Jan 1, 2008

Study Type

OBSERVATIONAL

Conditions

Summary

Hepatitis B virus (HBV) infection remains one of the most serious health problems worldwide. Patients with chronic HBV infection are at an increased risk for developing hepatic cirrhosis, hepatocellular carcinoma and even death. Although some predictive factors of the outcome of chronic HBV infection were identified, more precisely determine the factors which are associated with the outcome in non-selected patients with chronic HBV infection are still needed. The investigators purpose is to constitute a observational cohort of non-selected Chinese patients to create a database of epidemiological, clinical, biological, virological, immunologic and therapeutic parameters, in order to determine factors associated with the outcome of chronic HBV infection.


Eligibility

Inclusion Criteria1

  • Patients with chronic HBV infection (defined as HBsAg positive for at least 6 months)

Exclusion Criteria3

  • Co-infection with human immunodeficiency virus (HIV), hepatitis C virus (HCV) and/or hepatitis D virus (HDV)
  • History of liver transplantation
  • History of hepatocellular carcinoma (HCC)

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Locations(6)

The Third Hospital of Changzhou

Changzhou, Jiangsu, China

Huai'an No.4 People's Hospital

Huai'an, Jiangsu, China

The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School

Nanjing, Jiangsu, China

Nanjing Jiangbei People's Hospital

Nanjing, Jiangsu, China

Suqian People's Hospital

Suqian, Jiangsu, China

The Fifth People's Hospital of Suzhou

Suzhou, Jiangsu, China

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NCT03097952


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